8r5i
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==In situ structure of the Vaccinia virus (WR) A4/A10 palisade trimer in mature virions by flexible fitting into a cryoET map== | |
| + | <StructureSection load='8r5i' size='340' side='right'caption='[[8r5i]], [[Resolution|resolution]] 9.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8r5i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_WR Vaccinia virus WR]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8R5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8R5I FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.7Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8r5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8r5i OCA], [https://pdbe.org/8r5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8r5i RCSB], [https://www.ebi.ac.uk/pdbsum/8r5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8r5i ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PG130_VACCW PG130_VACCW] Component of the virion core. Participates in virion assembly.<ref>PMID:10600608</ref> <ref>PMID:11799179</ref> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Poxviruses such as variola virus (smallpox) and monkeypox cause diseases in humans. Other poxviruses, including vaccinia and modified vaccinia Ankara, are used as vaccine vectors. Given their importance, a greater structural understanding of poxvirus virions is needed. We now performed cryo-electron tomography of purified intact vaccinia virions to study the structure of the palisade, a protein lattice that defines the viral core boundary. We identified the main viral proteins that form the palisade and their interaction surfaces and provided new insights into the organization of the viral core. | ||
| - | + | Palisade structure in intact vaccinia virions.,Hernandez-Gonzalez M, Calcraft T, Nans A, Rosenthal PB, Way M mBio. 2024 Jan 3:e0313423. doi: 10.1128/mbio.03134-23. PMID:38171004<ref>PMID:38171004</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 8r5i" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vaccinia virus WR]] | ||
| + | [[Category: Calcraft T]] | ||
| + | [[Category: Hernandez-Gonzalez M]] | ||
| + | [[Category: Nans A]] | ||
| + | [[Category: Rosenthal PB]] | ||
| + | [[Category: Way M]] | ||
Revision as of 10:27, 10 January 2024
In situ structure of the Vaccinia virus (WR) A4/A10 palisade trimer in mature virions by flexible fitting into a cryoET map
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