Band 3
From Proteopedia
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==Band 3== | ==Band 3== | ||
| - | <StructureSection load='7rtm' size='340' side='right' caption='Band 3 dimer' scene=''> | + | <StructureSection load='7rtm' size='340' side='right' caption='Rabbit Band 3 dimer PDB code [[7rtm]].' scene=''> |
'''Anion exchanger 1''' (AE1), also known as '''band 3''' or '''SLC4A1''' or '''Band 3 anion transport protein''' exchanges chloride and bicarbonate across the red blood cell membrane, assisting in removing carbon dioxide from tissues. It also anchors the membrane skeleton <ref>PMID:34669510</ref>. Band 3's name comes from its appearance as the third major band on SDS-PAGE of red blood cell membrane proteins <ref>PMID: 4326772</ref>. | '''Anion exchanger 1''' (AE1), also known as '''band 3''' or '''SLC4A1''' or '''Band 3 anion transport protein''' exchanges chloride and bicarbonate across the red blood cell membrane, assisting in removing carbon dioxide from tissues. It also anchors the membrane skeleton <ref>PMID:34669510</ref>. Band 3's name comes from its appearance as the third major band on SDS-PAGE of red blood cell membrane proteins <ref>PMID: 4326772</ref>. | ||
Revision as of 10:37, 15 January 2024
Band 3
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References
- ↑ Jennings ML. Cell physiology and molecular mechanism of anion transport by erythrocyte band 3/AE1. Am J Physiol Cell Physiol. 2021 Dec 1;321(6):C1028-C1059. PMID:34669510 doi:10.1152/ajpcell.00275.2021
- ↑ Fairbanks G, Steck TL, Wallach DF. Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. Biochemistry. 1971 Jun 22;10(13):2606-17. PMID:4326772 doi:10.1021/bi00789a030
- ↑ Arakawa T, Kobayashi-Yurugi T, Alguel Y, Iwanari H, Hatae H, Iwata M, Abe Y, Hino T, Ikeda-Suno C, Kuma H, Kang D, Murata T, Hamakubo T, Cameron AD, Kobayashi T, Hamasaki N, Iwata S. Crystal structure of the anion exchanger domain of human erythrocyte band 3. Science. 2015 Nov 6;350(6261):680-4. doi: 10.1126/science.aaa4335. PMID:26542571 doi:http://dx.doi.org/10.1126/science.aaa4335
- ↑ Hatae H, Inaka K, Okamura R, Furubayashi N, Kamo M, Kobayashi T, Abe Y, Iwata S, Hamasaki N. Crystallization of Human Erythrocyte Band 3, the anion exchanger, at the International Space Station "KIBO". Anal Biochem. 2018 Oct 15;559:91-93. PMID:30118660 doi:10.1016/j.ab.2018.08.009
