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8hrv

From Proteopedia

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Current revision (10:05, 17 January 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8hrv is ON HOLD until 2024-12-16
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==dutpase of helicobacter pylori 26695==
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<StructureSection load='8hrv' size='340' side='right'caption='[[8hrv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors: Kumari, K., Gourinath, S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8hrv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HRV FirstGlance]. <br>
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Description: dutpase of helicobacter pylori 26695
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DUP:2-DEOXYURIDINE+5-ALPHA,BETA-IMIDO-TRIPHOSPHATE'>DUP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Kumari, K]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hrv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hrv OCA], [https://pdbe.org/8hrv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hrv RCSB], [https://www.ebi.ac.uk/pdbsum/8hrv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hrv ProSAT]</span></td></tr>
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[[Category: Gourinath, S]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DUT_HELPY DUT_HELPY] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
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__TOC__
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</StructureSection>
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[[Category: Helicobacter pylori 26695]]
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[[Category: Large Structures]]
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[[Category: Gourinath S]]
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[[Category: Kumari K]]

Current revision

dutpase of helicobacter pylori 26695

PDB ID 8hrv

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