8ivd
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==COMPLEX STRUCTURE OF CD93-IGFBP7== | |
| - | + | <StructureSection load='8ivd' size='340' side='right'caption='[[8ivd]], [[Resolution|resolution]] 3.24Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ivd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IVD FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.24Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ivd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ivd OCA], [https://pdbe.org/8ivd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ivd RCSB], [https://www.ebi.ac.uk/pdbsum/8ivd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ivd ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/IBP7_HUMAN IBP7_HUMAN] Familial retinal arterial macroaneurysm. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IBP7_HUMAN IBP7_HUMAN] Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.<ref>PMID:8117260</ref> <ref>PMID:8939990</ref> [https://www.uniprot.org/uniprot/C1QR1_HUMAN C1QR1_HUMAN] Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Song GJ]] | ||
| + | [[Category: Xu YM]] | ||
Revision as of 10:06, 17 January 2024
COMPLEX STRUCTURE OF CD93-IGFBP7
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