8qn3

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'''Unreleased structure'''
 
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The entry 8qn3 is ON HOLD until Paper Publication
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==OPR3 wildtype in complex with NADH4==
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<StructureSection load='8qn3' size='340' side='right'caption='[[8qn3]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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Authors: Bijelic, A., Macheroux, P., Keschbaumer, B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8qn3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_lycopersicum Solanum lycopersicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QN3 FirstGlance]. <br>
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Description: OPR3 wildtype in complex with NADH4
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=WI6:1,4,5,6-Tetrahydronicotinamide+adenine+dinucleotide'>WI6</scene></td></tr>
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[[Category: Keschbaumer, B]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qn3 OCA], [https://pdbe.org/8qn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qn3 RCSB], [https://www.ebi.ac.uk/pdbsum/8qn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qn3 ProSAT]</span></td></tr>
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[[Category: Bijelic, A]]
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</table>
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[[Category: Macheroux, P]]
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== Function ==
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[https://www.uniprot.org/uniprot/OPR3_SOLLC OPR3_SOLLC] Specifically cleaves olefinic bonds in cyclic enones. Involved in the biosynthesis of jasmonic acid (JA) and perhaps in biosynthesis or metabolism of other oxylipin signaling moleclules. It is required for the spatial and temporal regulation of JA levels during dehiscence of anthers, promoting the stomium degeneration program (By similarity). In vitro, reduces 9S,13S-12-oxophytodienoic acid (9S,13S-OPDA) and 9R,13R-OPDA to 9S,13S-OPC-8:0 and 9R,13R-OPC-8:0, respectively.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Solanum lycopersicum]]
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[[Category: Bijelic A]]
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[[Category: Keschbaumer B]]
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[[Category: Macheroux P]]

Revision as of 10:08, 17 January 2024

OPR3 wildtype in complex with NADH4

PDB ID 8qn3

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