2wzr

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Current revision (12:44, 17 January 2024) (edit) (undo)
 
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<StructureSection load='2wzr' size='340' side='right'caption='[[2wzr]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='2wzr' size='340' side='right'caption='[[2wzr]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wzr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus Foot-and-mouth disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WZR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wzr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_SAT_1 Foot-and-mouth disease virus SAT 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WZR FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wzr OCA], [https://pdbe.org/2wzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wzr RCSB], [https://www.ebi.ac.uk/pdbsum/2wzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wzr ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wzr OCA], [https://pdbe.org/2wzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wzr RCSB], [https://www.ebi.ac.uk/pdbsum/2wzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wzr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q6PMU1_9PICO Q6PMU1_9PICO]] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity). RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS001676_004_010047]
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[https://www.uniprot.org/uniprot/Q6PMU1_9PICO Q6PMU1_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity). RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS001676_004_010047]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Foot-and-mouth disease virus]]
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[[Category: Foot-and-mouth disease virus SAT 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Adams, P]]
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[[Category: Adams P]]
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[[Category: Blakemore, W]]
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[[Category: Blakemore W]]
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[[Category: Fry, E]]
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[[Category: Fry E]]
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[[Category: King, A]]
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[[Category: King A]]
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[[Category: Lea, S]]
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[[Category: Lea S]]
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[[Category: Newman, J]]
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[[Category: Newman J]]
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[[Category: Stuart, D]]
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[[Category: Stuart D]]
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[[Category: Capsid]]
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[[Category: Capsid protein]]
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[[Category: Host cytoplasmic vesicle]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Rna replication]]
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[[Category: Rna-directed rna polymerase]]
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[[Category: Virus]]
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Current revision

The Structure of Foot and Mouth Disease Virus Serotype SAT1

PDB ID 2wzr

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