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2xel

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Current revision (12:45, 17 January 2024) (edit) (undo)
 
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<StructureSection load='2xel' size='340' side='right'caption='[[2xel]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2xel' size='340' side='right'caption='[[2xel]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xel]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_11735 Atcc 11735]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xel]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=IA2:2,4-DICHLORO-6-(3,4,5-TRICHLORO-1H-PYRROL-2YL)PHENOL'>IA2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1mne|1mne]], [[1d1c|1d1c]], [[1jx2|1jx2]], [[1q5g|1q5g]], [[1w9l|1w9l]], [[1mmn|1mmn]], [[1d0y|1d0y]], [[1vom|1vom]], [[2aka|2aka]], [[2jhr|2jhr]], [[2jj9|2jj9]], [[1lvk|1lvk]], [[1w9j|1w9j]], [[1jwy|1jwy]], [[2x9h|2x9h]], [[1yv3|1yv3]], [[1fmv|1fmv]], [[1d0x|1d0x]], [[1fmw|1fmw]], [[1d1b|1d1b]], [[1g8x|1g8x]], [[1mma|1mma]], [[1d1a|1d1a]], [[1mmg|1mmg]], [[1w9i|1w9i]], [[1d0z|1d0z]], [[1mnd|1mnd]], [[1w9k|1w9k]], [[1mmd|1mmd]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=IA2:2,4-DICHLORO-6-(3,4,5-TRICHLORO-1H-PYRROL-2YL)PHENOL'>IA2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xel OCA], [https://pdbe.org/2xel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xel RCSB], [https://www.ebi.ac.uk/pdbsum/2xel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xel ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xel OCA], [https://pdbe.org/2xel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xel RCSB], [https://www.ebi.ac.uk/pdbsum/2xel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xel ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
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[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 11735]]
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[[Category: Dictyostelium discoideum]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chinthalapudi, K]]
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[[Category: Chinthalapudi K]]
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[[Category: Coluccio, L M]]
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[[Category: Coluccio LM]]
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[[Category: Fedorov, R]]
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[[Category: Fedorov R]]
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[[Category: Gutzeit, H O]]
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[[Category: Gutzeit HO]]
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[[Category: Hartmann, F K]]
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[[Category: Hartmann FK]]
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[[Category: Heissler, S M]]
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[[Category: Heissler SM]]
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[[Category: Knoelker, H J]]
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[[Category: Knoelker HJ]]
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[[Category: Manstein, D J]]
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[[Category: Manstein DJ]]
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[[Category: Martin, R]]
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[[Category: Martin R]]
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[[Category: Taft, M H]]
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[[Category: Taft MH]]
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[[Category: Tsiavaliaris, G]]
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[[Category: Tsiavaliaris G]]
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[[Category: Allosteric inhibitor]]
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[[Category: Contractile protein]]
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[[Category: Motor protein]]
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[[Category: Non-hydroylsable atp analogue]]
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Current revision

Molecular Mechanism of Pentachloropseudilin Mediated Inhibition of Myosin Motor Activity

PDB ID 2xel

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