Afatinib

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Afatinib, sold under the brand name Gilotrif among others, is a medication which is used to treat non-small cell lung carcinoma (NSCLC).<ref name="a2">Spreitzer H (13 May 2008). "Neue Wirkstoffe – Tovok". Österreichische Apothekerzeitung (in German) (10/2008): 498.</ref><ref name="a3">PMID:19037840</ref><ref name="a4">[https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/201292s014lbl.pdf "Gilotrif (afatinib)"] (PDF). US Food and Drug Administration. Retrieved 11 March 2021.</ref> It belongs to the tyrosine kinase inhibitor family of medications.<ref name="a5">[https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2013-PI-02417-1 "Giotrif Afatinib (as afatinib dimaleate)"] (PDF). TGA eBusiness Services. Boehringer Ingelheim Pty Limited. 7 November 2013. Retrieved 28 January 2014.</ref> See also [https://en.wikipedia.org/wiki/Afatinib Afatinib].
Afatinib, sold under the brand name Gilotrif among others, is a medication which is used to treat non-small cell lung carcinoma (NSCLC).<ref name="a2">Spreitzer H (13 May 2008). "Neue Wirkstoffe – Tovok". Österreichische Apothekerzeitung (in German) (10/2008): 498.</ref><ref name="a3">PMID:19037840</ref><ref name="a4">[https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/201292s014lbl.pdf "Gilotrif (afatinib)"] (PDF). US Food and Drug Administration. Retrieved 11 March 2021.</ref> It belongs to the tyrosine kinase inhibitor family of medications.<ref name="a5">[https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2013-PI-02417-1 "Giotrif Afatinib (as afatinib dimaleate)"] (PDF). TGA eBusiness Services. Boehringer Ingelheim Pty Limited. 7 November 2013. Retrieved 28 January 2014.</ref> See also [https://en.wikipedia.org/wiki/Afatinib Afatinib].

Revision as of 11:27, 21 January 2024

Afatinib

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References

  1. ↑ Spreitzer H (13 May 2008). "Neue Wirkstoffe – Tovok". Österreichische Apothekerzeitung (in German) (10/2008): 498.
  2. ↑ 2.0 2.1 Minkovsky N, Berezov A. BIBW-2992, a dual receptor tyrosine kinase inhibitor for the treatment of solid tumors. Curr Opin Investig Drugs. 2008 Dec;9(12):1336-46 PMID:19037840
  3. ↑ "Gilotrif (afatinib)" (PDF). US Food and Drug Administration. Retrieved 11 March 2021.
  4. ↑ "Giotrif Afatinib (as afatinib dimaleate)" (PDF). TGA eBusiness Services. Boehringer Ingelheim Pty Limited. 7 November 2013. Retrieved 28 January 2014.
  5. ↑ Li D, Ambrogio L, Shimamura T, Kubo S, Takahashi M, Chirieac LR, Padera RF, Shapiro GI, Baum A, Himmelsbach F, Rettig WJ, Meyerson M, Solca F, Greulich H, Wong KK. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene. 2008 Aug 7;27(34):4702-11. PMID:18408761 doi:10.1038/onc.2008.109
  6. ↑ Schubert-Zsilavecz, M, Wurglics, M, Neue Arzneimittel Frühjahr 2013. (in German)

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Alexander Berchansky, Michal Harel

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