6qwa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:09, 24 January 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6qwa' size='340' side='right'caption='[[6qwa]], [[Resolution|resolution]] 1.06&Aring;' scene=''>
<StructureSection load='6qwa' size='340' side='right'caption='[[6qwa]], [[Resolution|resolution]] 1.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6qwa]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QWA FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6qwa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QWA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QWA FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JJT:(2~{S})-5-azanylidene-2-(piperidin-4-ylcarbamoyl)piperidine-1-carboxylic+acid'>JJT</scene>, <scene name='pdbligand=MK7:(2S,5R)-1-FORMYL-N-(PIPERIDIN-4-YL)-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>MK7</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.06&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JJT:(2~{S})-5-azanylidene-2-(piperidin-4-ylcarbamoyl)piperidine-1-carboxylic+acid'>JJT</scene>, <scene name='pdbligand=MK7:(2S,5R)-1-FORMYL-N-(PIPERIDIN-4-YL)-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>MK7</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwa OCA], [http://pdbe.org/6qwa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qwa RCSB], [http://www.ebi.ac.uk/pdbsum/6qwa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwa ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qwa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qwa OCA], [https://pdbe.org/6qwa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qwa RCSB], [https://www.ebi.ac.uk/pdbsum/6qwa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qwa ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 19:
</div>
</div>
<div class="pdbe-citations 6qwa" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6qwa" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-lactamase]]
+
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Hinchliffe, P]]
+
[[Category: Hinchliffe P]]
-
[[Category: Spencer, J]]
+
[[Category: Spencer J]]
-
[[Category: Tooke, C L]]
+
[[Category: Tooke CL]]
-
[[Category: Antibiotic resistance]]
+
-
[[Category: Antimicrobial protein]]
+
-
[[Category: Diazabicyclooctane]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Relebactam]]
+

Current revision

Crystal structure of KPC-3 complexed with relebactam (16 hour soak)

PDB ID 6qwa

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6qwa"
Personal tools