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6rv7

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Current revision (12:29, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6rv7' size='340' side='right'caption='[[6rv7]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
<StructureSection load='6rv7' size='340' side='right'caption='[[6rv7]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6rv7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RV7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RV7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6rv7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cerrena_unicolor Cerrena unicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RV7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BXP:4-O-BETA-D-XYLOPYRANOSYL-BETA-D-XYLOPYRANOSE'>BXP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GCV:4-O-METHYL-ALPHA-D-GLUCURONIC+ACID'>GCV</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XYL:D-XYLITOL'>XYL</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6rtv|6rtv]], [[6ru1|6ru1]], [[6ru2|6ru2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GCV:4-O-METHYL-ALPHA-D-GLUCURONIC+ACID'>GCV</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PRD_900116:4beta-beta-xylobiose'>PRD_900116</scene>, <scene name='pdbligand=XYL:D-XYLITOL'>XYL</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rv7 OCA], [http://pdbe.org/6rv7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rv7 RCSB], [http://www.ebi.ac.uk/pdbsum/6rv7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rv7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rv7 OCA], [https://pdbe.org/6rv7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rv7 RCSB], [https://www.ebi.ac.uk/pdbsum/6rv7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rv7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GCE_CERUI GCE_CERUI]] Glucuronoyl esterase which may play a significant role in biomass degradation, as it is considered to disconnect hemicellulose from lignin through the hydrolysis of the ester bond between 4-O-methyl-D-glucuronic acid residues of glucuronoxylans and aromatic alcohols of lignin (PubMed:25425346, PubMed:26712478).<ref>PMID:25425346</ref> <ref>PMID:26712478</ref>
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[https://www.uniprot.org/uniprot/GCE_CERUI GCE_CERUI] Glucuronoyl esterase which may play a significant role in biomass degradation, as it is considered to disconnect hemicellulose from lignin through the hydrolysis of the ester bond between 4-O-methyl-D-glucuronic acid residues of glucuronoxylans and aromatic alcohols of lignin (PubMed:25425346, PubMed:26712478).<ref>PMID:25425346</ref> <ref>PMID:26712478</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6rv7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6rv7" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Methylesterase 3D structures|Methylesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cerrena unicolor]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Agger, J W]]
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[[Category: Agger JW]]
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[[Category: Ernst, H A]]
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[[Category: Ernst HA]]
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[[Category: Langkilde, A]]
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[[Category: Langkilde A]]
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[[Category: Larsen, S]]
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[[Category: Larsen S]]
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[[Category: Meyer, A]]
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[[Category: Meyer A]]
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[[Category: Mosbech, C]]
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[[Category: Mosbech C]]
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[[Category: Westh, P]]
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[[Category: Westh P]]
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[[Category: Alpha/beta-hydrolase]]
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[[Category: Ce15]]
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[[Category: Esterase]]
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[[Category: Hydrolase]]
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[[Category: Ligand-bound]]
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Current revision

Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant in complex with the aldouronic acid UXXR

PDB ID 6rv7

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