6s4m

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Current revision (12:35, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='6s4m' size='340' side='right'caption='[[6s4m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6s4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S4M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6s4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S4M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MFSD10, TETRAN ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s4m OCA], [https://pdbe.org/6s4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s4m RCSB], [https://www.ebi.ac.uk/pdbsum/6s4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s4m ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s4m OCA], [https://pdbe.org/6s4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s4m RCSB], [https://www.ebi.ac.uk/pdbsum/6s4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s4m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MFS10_HUMAN MFS10_HUMAN]] Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.<ref>PMID:17362938</ref>
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[https://www.uniprot.org/uniprot/MFS10_HUMAN MFS10_HUMAN] Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump.<ref>PMID:17362938</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Burgess-Brown, N A]]
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[[Category: Burgess-Brown NA]]
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[[Category: Bushell, S R]]
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[[Category: Bushell SR]]
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[[Category: Carpenter, E P]]
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[[Category: Carpenter EP]]
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[[Category: Chalk, R]]
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[[Category: Chalk R]]
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[[Category: Chu, A]]
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[[Category: Chu A]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Mukhopadhyay, S M.M]]
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[[Category: Mukhopadhyay SMM]]
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[[Category: Pascoa, T C]]
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[[Category: Pascoa TC]]
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[[Category: Pike, A C.W]]
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[[Category: Pike ACW]]
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[[Category: Quigley, A]]
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[[Category: Quigley A]]
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[[Category: Structural genomic]]
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[[Category: Shrestha L]]
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[[Category: Shrestha, L]]
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[[Category: Venkaya S]]
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[[Category: Venkaya, S]]
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[[Category: Amtf1]]
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[[Category: Membrane transporter]]
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[[Category: Mfsd10]]
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[[Category: Sgc]]
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[[Category: Slc22a32]]
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[[Category: Tetran]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of the human organic anion transporter MFSD10 (TETRAN)

PDB ID 6s4m

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