6sbq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:39, 24 January 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6sbq' size='340' side='right'caption='[[6sbq]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
<StructureSection load='6sbq' size='340' side='right'caption='[[6sbq]], [[Resolution|resolution]] 1.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6sbq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SBQ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6sbq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SBQ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7ML:[(7~{S})-6,6-BIS(OXIDANYL)-4-PHENYL-5,7,8,9-TETRAHYDROBENZO[7]ANNULEN-7-YL]AZANIUM'>7ML</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.33&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7ML:[(7~{S})-6,6-BIS(OXIDANYL)-4-PHENYL-5,7,8,9-TETRAHYDROBENZO[7]ANNULEN-7-YL]AZANIUM'>7ML</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sbq OCA], [http://pdbe.org/6sbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sbq RCSB], [http://www.ebi.ac.uk/pdbsum/6sbq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sbq ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6sbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sbq OCA], [https://pdbe.org/6sbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6sbq RCSB], [https://www.ebi.ac.uk/pdbsum/6sbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6sbq ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 19:
</div>
</div>
<div class="pdbe-citations 6sbq" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6sbq" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 22: Line 27:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Membrane alanyl aminopeptidase]]
+
[[Category: Plasmodium falciparum 3D7]]
-
[[Category: Alavi, S]]
+
[[Category: Alavi S]]
-
[[Category: Albrecht, S]]
+
[[Category: Albrecht S]]
-
[[Category: Cavarelli, J]]
+
[[Category: Cavarelli J]]
-
[[Category: Florent, I]]
+
[[Category: Florent I]]
-
[[Category: McEwen, A G]]
+
[[Category: McEwen AG]]
-
[[Category: Mouray, E]]
+
[[Category: Mouray E]]
-
[[Category: Poussin-Courmontagne, P]]
+
[[Category: Poussin-Courmontagne P]]
-
[[Category: Salomon, E]]
+
[[Category: Salomon E]]
-
[[Category: Schmitt, M]]
+
[[Category: Schmitt M]]
-
[[Category: Tarnus, C]]
+
[[Category: Tarnus C]]
-
[[Category: Torchy, M]]
+
[[Category: Torchy M]]
-
[[Category: Hydrolase]]
+
-
[[Category: M1 aminopeptidase]]
+

Current revision

The crystal structure of PfA-M1 in complex with 7-amino-4-phenyl-5,7,8,9-tetrahydrobenzocyclohepten-6-one

PDB ID 6sbq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6sbq"
Personal tools