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6t0j

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Current revision (12:51, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6t0j' size='340' side='right'caption='[[6t0j]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='6t0j' size='340' side='right'caption='[[6t0j]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6t0j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T0J OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6T0J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6t0j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T0J FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cyp124, Rv2266, MTCY339.44c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6t0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t0j OCA], [http://pdbe.org/6t0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6t0j RCSB], [http://www.ebi.ac.uk/pdbsum/6t0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6t0j ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t0j OCA], [https://pdbe.org/6t0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t0j RCSB], [https://www.ebi.ac.uk/pdbsum/6t0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t0j ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CP124_MYCTU CP124_MYCTU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Borshchevskiy, V]]
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[[Category: Borshchevskiy V]]
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[[Category: Bukhdruker, S]]
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[[Category: Bukhdruker S]]
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[[Category: Gilep, A]]
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[[Category: Gilep A]]
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[[Category: Marin, E]]
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[[Category: Marin E]]
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[[Category: Strushkevich, N]]
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[[Category: Strushkevich N]]
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[[Category: Varaksa, T]]
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[[Category: Varaksa T]]
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[[Category: Antituberculosis]]
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[[Category: Cyp]]
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[[Category: Cytochrome]]
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[[Category: Drug]]
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[[Category: Mmpl3]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Oxidoreductase]]
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[[Category: P450]]
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[[Category: Sq]]
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[[Category: Sq109]]
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[[Category: Substrate]]
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[[Category: Tuberculosis]]
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Current revision

Crystal structure of CYP124 in complex with SQ109

PDB ID 6t0j

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