6t97

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<StructureSection load='6t97' size='340' side='right'caption='[[6t97]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='6t97' size='340' side='right'caption='[[6t97]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6t97]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leiin Leiin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T97 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6t97]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_infantum Leishmania infantum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T97 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MWW:4-[1-[4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]-3-(2-piperidin-4-ylethoxy)phenyl]-1,2,3-triazol-4-yl]butan-1-amine'>MWW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6t95|6t95]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MWW:4-[1-[4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]-3-(2-piperidin-4-ylethoxy)phenyl]-1,2,3-triazol-4-yl]butan-1-amine'>MWW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TRYR, LINF_050008500, LINJ_05_0350 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5671 LEIIN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Trypanothione-disulfide_reductase Trypanothione-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.12 1.8.1.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t97 OCA], [https://pdbe.org/6t97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t97 RCSB], [https://www.ebi.ac.uk/pdbsum/6t97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t97 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t97 OCA], [https://pdbe.org/6t97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t97 RCSB], [https://www.ebi.ac.uk/pdbsum/6t97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t97 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A4HSF7_LEIIN A4HSF7_LEIIN]
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Leiin]]
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[[Category: Leishmania infantum]]
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[[Category: Trypanothione-disulfide reductase]]
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[[Category: Carriles A]]
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[[Category: Carriles, A]]
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[[Category: Hermoso JA]]
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[[Category: Hermoso, J A]]
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[[Category: Complex]]
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[[Category: Drug]]
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[[Category: Flavoprotein]]
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[[Category: Inhibitor]]
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[[Category: Leishmania]]
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[[Category: Oxidoreductase]]
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Revision as of 12:58, 24 January 2024

Trypanothione Reductase from Leismania infantum in complex with TRL190

PDB ID 6t97

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