6th4

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Current revision (13:02, 24 January 2024) (edit) (undo)
 
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====
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==Tubulin-inhibitor complex==
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<StructureSection load='6th4' size='340' side='right'caption='[[6th4]]' scene=''>
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<StructureSection load='6th4' size='340' side='right'caption='[[6th4]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6th4]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TH4 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6th4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6th4 OCA], [https://pdbe.org/6th4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6th4 RCSB], [https://www.ebi.ac.uk/pdbsum/6th4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6th4 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.121&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=N9B:1,2,3,9-tetramethoxy-6-methylidene-5~{H}-cyclohepta[a]naphthalen-8-one'>N9B</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6th4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6th4 OCA], [https://pdbe.org/6th4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6th4 RCSB], [https://www.ebi.ac.uk/pdbsum/6th4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6th4 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/STMN4_RAT STMN4_RAT] Exhibits microtubule-destabilizing activity.<ref>PMID:15039434</ref> <ref>PMID:12111843</ref> <ref>PMID:15014504</ref>
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==See Also==
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*[[Stathmin-4 3D structures|Stathmin-4 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Ovis aries]]
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[[Category: Rattus norvegicus]]
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[[Category: Gigant B]]
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[[Category: Varela PF]]

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Tubulin-inhibitor complex

PDB ID 6th4

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