6tsz
From Proteopedia
(Difference between revisions)
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<StructureSection load='6tsz' size='340' side='right'caption='[[6tsz]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='6tsz' size='340' side='right'caption='[[6tsz]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[6tsz]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[6tsz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TSZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TSZ FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tsz OCA], [https://pdbe.org/6tsz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tsz RCSB], [https://www.ebi.ac.uk/pdbsum/6tsz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tsz ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Disease == | == Disease == | ||
- | [ | + | [https://www.uniprot.org/uniprot/ULK4_HUMAN ULK4_HUMAN] Various anomalies in ULK4 gene have been reported for several cases of schizophrenia, schizophrenia plus bipolar disorder and autism. ULK4 gene has been proposed to be a rare susceptibility risk factor for a range of psychiatric diseases including schizophrenia.<ref>PMID:24284070</ref> |
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/ULK4_HUMAN ULK4_HUMAN] May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.<ref>PMID:24284070</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | + | [[Category: Arrowsmith CH]] | |
- | [[Category: Arrowsmith | + | [[Category: Bountra C]] |
- | [[Category: Bountra | + | [[Category: Chatterjee D]] |
- | [[Category: Chatterjee | + | [[Category: Edwards AM]] |
- | [[Category: Edwards | + | [[Category: Knapp S]] |
- | [[Category: Knapp | + | [[Category: Mathea S]] |
- | [[Category: Mathea | + | [[Category: Preuss F]] |
- | [[Category: Preuss | + | |
- | + | ||
- | + |
Current revision
The ULK4 Pseudokinase Domain Bound To ATPgammaS
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