6xuf
From Proteopedia
(Difference between revisions)
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==HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21== | ==HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21== | ||
| - | <StructureSection load='6xuf' size='340' side='right'caption='[[6xuf]]' scene=''> | + | <StructureSection load='6xuf' size='340' side='right'caption='[[6xuf]], [[Resolution|resolution]] 1.24Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XUF FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6xuf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XUF FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xuf OCA], [https://pdbe.org/6xuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xuf RCSB], [https://www.ebi.ac.uk/pdbsum/6xuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xuf ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.241Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=O1E:5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine'>O1E</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xuf OCA], [https://pdbe.org/6xuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xuf RCSB], [https://www.ebi.ac.uk/pdbsum/6xuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xuf ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Pyrococcus furiosus DSM 3638]] | ||
[[Category: Hyvonen ME]] | [[Category: Hyvonen ME]] | ||
[[Category: Marsh ME]] | [[Category: Marsh ME]] | ||
[[Category: Scott DE]] | [[Category: Scott DE]] | ||
Current revision
HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21
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