6xum
From Proteopedia
(Difference between revisions)
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==Human Aldose Reductase Mutant L300/301A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)== | ==Human Aldose Reductase Mutant L300/301A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)== | ||
| - | <StructureSection load='6xum' size='340' side='right'caption='[[6xum]]' scene=''> | + | <StructureSection load='6xum' size='340' side='right'caption='[[6xum]], [[Resolution|resolution]] 0.97Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XUM FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6xum]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XUM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XUM FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xum OCA], [https://pdbe.org/6xum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xum RCSB], [https://www.ebi.ac.uk/pdbsum/6xum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xum ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.97Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=30L:{5-FLUORO-2-[(3-NITROBENZYL)CARBAMOYL]PHENOXY}ACETIC+ACID'>30L</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xum FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xum OCA], [https://pdbe.org/6xum PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xum RCSB], [https://www.ebi.ac.uk/pdbsum/6xum PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xum ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Aldose reductase 3D structures|Aldose reductase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Heine A]] | [[Category: Heine A]] | ||
Current revision
Human Aldose Reductase Mutant L300/301A in Complex with a Ligand with an IDD Structure ({5-fluoro-2-[(3-nitrobenzyl)carbamoyl]phenoxy}acetic acid)
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Categories: Homo sapiens | Large Structures | Heine A | Hubert L-S | Klebe G | Ley M
