6y4i
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin== | ==Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin== | ||
| - | <StructureSection load='6y4i' size='340' side='right'caption='[[6y4i]]' scene=''> | + | <StructureSection load='6y4i' size='340' side='right'caption='[[6y4i]], [[Resolution|resolution]] 1.16Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y4I FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6y4i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y4I FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y4i OCA], [https://pdbe.org/6y4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y4i RCSB], [https://www.ebi.ac.uk/pdbsum/6y4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y4i ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.16Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0PK:N-[(S)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-PHENYLETHYL](HYDROXY)PHOSPHORYL]-L-LEUCYL-L-ALANINE'>0PK</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CS:CESIUM+ION'>CS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y4i OCA], [https://pdbe.org/6y4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y4i RCSB], [https://www.ebi.ac.uk/pdbsum/6y4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y4i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/THER_GEOSE THER_GEOSE] Extracellular zinc metalloprotease.<ref>PMID:3149972</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Thermolysin 3D structures|Thermolysin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Geobacillus stearothermophilus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Heine A]] | [[Category: Heine A]] | ||
[[Category: Klebe G]] | [[Category: Klebe G]] | ||
[[Category: Kljajic M]] | [[Category: Kljajic M]] | ||
Current revision
Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin
| |||||||||||
