4ojx

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<StructureSection load='4ojx' size='340' side='right'caption='[[4ojx]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
<StructureSection load='4ojx' size='340' side='right'caption='[[4ojx]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ojx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OJX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ojx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OJX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.31&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4ojv|4ojv]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE1, YGL248W, NRB369 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ojx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ojx OCA], [https://pdbe.org/4ojx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ojx RCSB], [https://www.ebi.ac.uk/pdbsum/4ojx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ojx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ojx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ojx OCA], [https://pdbe.org/4ojx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ojx RCSB], [https://www.ebi.ac.uk/pdbsum/4ojx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ojx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PDE1_YEAST PDE1_YEAST]] Controls the level of cAMP in yeast cells, together with the high-affinity cAMP phosphodiesterase (PDE2).
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[https://www.uniprot.org/uniprot/PDE1_YEAST PDE1_YEAST] Controls the level of cAMP in yeast cells, together with the high-affinity cAMP phosphodiesterase (PDE2).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
 
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cui, W]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Huang, M]]
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[[Category: Cui W]]
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[[Category: Ke, H]]
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[[Category: Huang M]]
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[[Category: Robinson, H]]
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[[Category: Ke H]]
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[[Category: Tian, Y]]
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[[Category: Robinson H]]
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[[Category: Wan, Y]]
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[[Category: Tian Y]]
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[[Category: Wang, Y]]
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[[Category: Wan Y]]
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[[Category: Cgmp and camp]]
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[[Category: Wang Y]]
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[[Category: Dual specificity]]
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[[Category: Hydrolase]]
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[[Category: Phosphodiesterase]]
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[[Category: Yeast pde]]
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Revision as of 14:19, 24 January 2024

crystal structure of yeast phosphodiesterase-1 in complex with GMP

PDB ID 4ojx

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