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5q0c
From Proteopedia
(Difference between revisions)
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==Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylurea and with fructose-2,6-diphosphate== | ==Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylurea and with fructose-2,6-diphosphate== | ||
| - | <StructureSection load='5q0c' size='340' side='right' caption='[[5q0c]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='5q0c' size='340' side='right'caption='[[5q0c]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5q0c]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5q0c]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Q0C FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=96G:N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-(4-methoxyphenyl)thiophene-2-sulfonamide'>96G</scene>, <scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=96G:N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-(4-methoxyphenyl)thiophene-2-sulfonamide'>96G</scene>, <scene name='pdbligand=FDP:FRUCTOSE-2,6-DIPHOSPHATE'>FDP</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5q0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q0c OCA], [https://pdbe.org/5q0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5q0c RCSB], [https://www.ebi.ac.uk/pdbsum/5q0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5q0c ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/F16P2_HUMAN F16P2_HUMAN] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Fructose-1%2C6-bisphosphatase 3D structures|Fructose-1%2C6-bisphosphatase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Alker | + | [[Category: Alker A]] |
| - | [[Category: Banner | + | [[Category: Banner D]] |
| - | [[Category: Benz | + | [[Category: Benz J]] |
| - | [[Category: Burley | + | [[Category: Burley SK]] |
| - | [[Category: Joseph | + | [[Category: Joseph C]] |
| - | [[Category: Kuhn | + | [[Category: Kuhn B]] |
| - | [[Category: Rudolph | + | [[Category: Rudolph MG]] |
| - | [[Category: Ruf | + | [[Category: Ruf A]] |
| - | [[Category: Shao | + | [[Category: Shao C]] |
| - | [[Category: Tetaz | + | [[Category: Tetaz T]] |
| - | [[Category: Yang | + | [[Category: Yang H]] |
| - | + | ||
| - | + | ||
Current revision
Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylurea and with fructose-2,6-diphosphate
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Categories: Homo sapiens | Large Structures | Alker A | Banner D | Benz J | Burley SK | Joseph C | Kuhn B | Rudolph MG | Ruf A | Shao C | Tetaz T | Yang H
