5q5r

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Current revision (14:33, 24 January 2024) (edit) (undo)
 
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<StructureSection load='5q5r' size='340' side='right'caption='[[5q5r]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
<StructureSection load='5q5r' size='340' side='right'caption='[[5q5r]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5q5r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q5R OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5Q5R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5q5r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Q5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Q5R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5q5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q5r OCA], [http://pdbe.org/5q5r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5q5r RCSB], [http://www.ebi.ac.uk/pdbsum/5q5r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5q5r ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5q5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5q5r OCA], [https://pdbe.org/5q5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5q5r RCSB], [https://www.ebi.ac.uk/pdbsum/5q5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5q5r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN]] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
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[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Aitkenhead, H]]
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[[Category: Aitkenhead H]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Burgess-Brown, N]]
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[[Category: Burgess-Brown N]]
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[[Category: Delft, F von]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Gileadi O]]
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[[Category: Gileadi, O]]
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[[Category: Krojer T]]
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[[Category: Krojer, T]]
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[[Category: Kupinska K]]
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[[Category: Kupinska, K]]
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[[Category: Lee SY]]
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[[Category: Lee, S Y]]
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[[Category: Newman JA]]
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[[Category: Newman, J A]]
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[[Category: Tallon R]]
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[[Category: Tallon, R]]
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[[Category: Von Delft F]]
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[[Category: Hydrolase]]
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[[Category: Pandda]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Xchemexplorer]]
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Current revision

PanDDA analysis group deposition -- Crystal Structure of DCLRE1A after initial refinement with no ligand modelled (structure 128)

PDB ID 5q5r

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