8txr
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==E. coli ExoVII(H238A)== | |
| - | + | <StructureSection load='8txr' size='340' side='right'caption='[[8txr]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8txr]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TXR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TXR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8txr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8txr OCA], [https://pdbe.org/8txr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8txr RCSB], [https://www.ebi.ac.uk/pdbsum/8txr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8txr ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EX7S_ECOLI EX7S_ECOLI] Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. It can degrade 3' or 5' ss regions extending from the termini of duplex DNA molecules and displaced ss regions. It can also excise thymine dimers in vitro (PubMed:4602029, PubMed:4602030, PubMed:22718974) (Probable). Required for production of the mature 5'-end of retron Ec78 or Ec83 msDNA. When in excess of the large subunit, counteracts the large subunit's toxicity (PubMed:26626352).<ref>PMID:22718974</ref> <ref>PMID:26626352</ref> <ref>PMID:4602029</ref> <ref>PMID:4602030</ref> <ref>PMID:6284744</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chuan L]] | ||
| + | [[Category: James MB]] | ||
Revision as of 11:46, 1 February 2024
E. coli ExoVII(H238A)
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