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7a3r

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Current revision (12:03, 1 February 2024) (edit) (undo)
 
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<StructureSection load='7a3r' size='340' side='right'caption='[[7a3r]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
<StructureSection load='7a3r' size='340' side='right'caption='[[7a3r]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7a3r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A3R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7a3r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A3R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7a3o|7a3o]], [[7a3s|7a3s]], [[7a3n|7a3n]], [[7a3u|7a3u]], [[7a3q|7a3q]], [[7a3p|7a3p]], [[7a3t|7a3t]], [[7cth|7cth]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a3r OCA], [https://pdbe.org/7a3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a3r RCSB], [https://www.ebi.ac.uk/pdbsum/7a3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a3r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a3r OCA], [https://pdbe.org/7a3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a3r RCSB], [https://www.ebi.ac.uk/pdbsum/7a3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a3r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/B1N6C5_9FLAV B1N6C5_9FLAV]] Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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[https://www.uniprot.org/uniprot/B1N6C5_9FLAV B1N6C5_9FLAV] Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dengue virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Duquerroy, S]]
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[[Category: Duquerroy S]]
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[[Category: Guardado-Calvo, P]]
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[[Category: Guardado-Calvo P]]
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[[Category: Rey, F A]]
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[[Category: Rey FA]]
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[[Category: Rouvinski, A]]
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[[Category: Rouvinski A]]
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[[Category: Sharma, A]]
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[[Category: Sharma A]]
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[[Category: Vaney, M C]]
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[[Category: Vaney MC]]
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[[Category: Antibody]]
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[[Category: Class 2 fusion protein]]
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[[Category: Dengue]]
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[[Category: Flavivirus]]
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[[Category: Viral protein]]
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Current revision

Crystal structure of dengue 1 virus envelope glycoprotein

PDB ID 7a3r

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