7av9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:16, 1 February 2024) (edit) (undo)
 
Line 1: Line 1:
==Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2==
==Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2==
-
<StructureSection load='7av9' size='340' side='right'caption='[[7av9]]' scene=''>
+
<StructureSection load='7av9' size='340' side='right'caption='[[7av9]], [[Resolution|resolution]] 1.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AV9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7AV9 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7av9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AV9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AV9 FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7av9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7av9 OCA], [http://pdbe.org/7av9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7av9 RCSB], [http://www.ebi.ac.uk/pdbsum/7av9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7av9 ProSAT]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.23&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7av9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7av9 OCA], [https://pdbe.org/7av9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7av9 RCSB], [https://www.ebi.ac.uk/pdbsum/7av9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7av9 ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref>
 +
 +
==See Also==
 +
*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]]
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith CH]]

Current revision

Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2

PDB ID 7av9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools