7b6o

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==Crystal structure of E.coli MurE mutant - C269S C340S C450S==
==Crystal structure of E.coli MurE mutant - C269S C340S C450S==
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<StructureSection load='7b6o' size='340' side='right'caption='[[7b6o]]' scene=''>
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<StructureSection load='7b6o' size='340' side='right'caption='[[7b6o]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B6O OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=7B6O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7b6o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7B6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7B6O FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=7b6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b6o OCA], [http://pdbe.org/7b6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=7b6o RCSB], [http://www.ebi.ac.uk/pdbsum/7b6o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=7b6o ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7b6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7b6o OCA], [https://pdbe.org/7b6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7b6o RCSB], [https://www.ebi.ac.uk/pdbsum/7b6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7b6o ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MURE_ECOLI MURE_ECOLI] Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine.<ref>PMID:2269304</ref> <ref>PMID:3905407</ref> <ref>PMID:11124264</ref>
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==See Also==
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*[[Mur ligase|Mur ligase]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Arrowsmith CH]]

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Crystal structure of E.coli MurE mutant - C269S C340S C450S

PDB ID 7b6o

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