7ba0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:24, 1 February 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='7ba0' size='340' side='right'caption='[[7ba0]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
<StructureSection load='7ba0' size='340' side='right'caption='[[7ba0]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7ba0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BA0 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7ba0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BA0 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=T5H:2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-20,21-dihydroxy-25,28-dimethoxy-11,18,23-trioxa-4-azatetracyclo[22.2.2.113,17.04,9]nonacosa-1(26),13(29),14,16,24,27-hexaene-3,10-dione'>T5H</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FKBP5, AIG6, FKBP51 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=T5H:2-cyclohexyl-12-[2-(3,4-dimethoxyphenyl)ethyl]-20,21-dihydroxy-25,28-dimethoxy-11,18,23-trioxa-4-azatetracyclo[22.2.2.113,17.04,9]nonacosa-1(26),13(29),14,16,24,27-hexaene-3,10-dione'>T5H</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ba0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ba0 OCA], [https://pdbe.org/7ba0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ba0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ba0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ba0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ba0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ba0 OCA], [https://pdbe.org/7ba0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ba0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ba0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ba0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN]] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
+
[https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 7ba0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7ba0" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[FKBP 3D structures|FKBP 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Peptidylprolyl isomerase]]
+
[[Category: Bauder M]]
-
[[Category: Bauder, M]]
+
[[Category: Hausch F]]
-
[[Category: Hausch, F]]
+
[[Category: Heymann T]]
-
[[Category: Heymann, T]]
+
[[Category: Merz S]]
-
[[Category: Merz, S]]
+
[[Category: Meyners C]]
-
[[Category: Meyners, C]]
+
[[Category: Purder P]]
-
[[Category: Purder, P]]
+
[[Category: Voll A]]
-
[[Category: Voll, A]]
+
-
[[Category: Complex]]
+
-
[[Category: Fkbp]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Isomerase]]
+
-
[[Category: Safit]]
+

Current revision

Structure of the FKBP51FK1 domain in complex with the macrocyclic SAFit analogue 63

PDB ID 7ba0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools