7nos
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of Mycobacterium tuberculosis ArgF in complex with 4-bromo-6-(trifluoromethyl)-1H-benzo[d]imidazole.== | ==Crystal structure of Mycobacterium tuberculosis ArgF in complex with 4-bromo-6-(trifluoromethyl)-1H-benzo[d]imidazole.== | ||
| - | <StructureSection load='7nos' size='340' side='right'caption='[[7nos]]' scene=''> | + | <StructureSection load='7nos' size='340' side='right'caption='[[7nos]], [[Resolution|resolution]] 1.77Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NOS FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7nos]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NOS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NOS FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nos OCA], [https://pdbe.org/7nos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nos RCSB], [https://www.ebi.ac.uk/pdbsum/7nos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nos ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UJZ:4-bromanyl-6-(trifluoromethyl)-1~{H}-benzimidazole'>UJZ</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nos FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nos OCA], [https://pdbe.org/7nos PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nos RCSB], [https://www.ebi.ac.uk/pdbsum/7nos PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nos ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/OTC_MYCTU OTC_MYCTU] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Blundell TL]] | [[Category: Blundell TL]] | ||
[[Category: Burgess A]] | [[Category: Burgess A]] | ||
Current revision
Crystal structure of Mycobacterium tuberculosis ArgF in complex with 4-bromo-6-(trifluoromethyl)-1H-benzo[d]imidazole.
| |||||||||||
