7o04
From Proteopedia
(Difference between revisions)
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==Crystal structure of a shortened IpgC variant in complex with [(2-chloro-5-nitrophenyl)methyl](methyl)amine== | ==Crystal structure of a shortened IpgC variant in complex with [(2-chloro-5-nitrophenyl)methyl](methyl)amine== | ||
| - | <StructureSection load='7o04' size='340' side='right'caption='[[7o04]]' scene=''> | + | <StructureSection load='7o04' size='340' side='right'caption='[[7o04]], [[Resolution|resolution]] 1.74Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O04 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7o04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O04 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o04 OCA], [https://pdbe.org/7o04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o04 RCSB], [https://www.ebi.ac.uk/pdbsum/7o04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o04 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4AV:1-(2-CHLORO-5-NITROPHENYL)-N-METHYLMETHANAMINE'>4AV</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o04 OCA], [https://pdbe.org/7o04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o04 RCSB], [https://www.ebi.ac.uk/pdbsum/7o04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o04 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Shigella flexneri]] | ||
[[Category: Gardonyi M]] | [[Category: Gardonyi M]] | ||
[[Category: Heine A]] | [[Category: Heine A]] | ||
[[Category: Klebe G]] | [[Category: Klebe G]] | ||
Current revision
Crystal structure of a shortened IpgC variant in complex with [(2-chloro-5-nitrophenyl)methyl](methyl)amine
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