7ocb
From Proteopedia
(Difference between revisions)
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==Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B== | ==Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B== | ||
| - | <StructureSection load='7ocb' size='340' side='right'caption='[[7ocb]]' scene=''> | + | <StructureSection load='7ocb' size='340' side='right'caption='[[7ocb]], [[Resolution|resolution]] 1.42Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OCB FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7ocb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OCB FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ocb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ocb OCA], [https://pdbe.org/7ocb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ocb RCSB], [https://www.ebi.ac.uk/pdbsum/7ocb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ocb ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=V88:7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine'>V88</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ocb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ocb OCA], [https://pdbe.org/7ocb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ocb RCSB], [https://www.ebi.ac.uk/pdbsum/7ocb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ocb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Spindlin|Spindlin]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Jin J]] | [[Category: Jin J]] | ||
Current revision
Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B
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Categories: Homo sapiens | Large Structures | Jin J | Johansson C | Krojer T | Oppermann U | Park K | Xiong Y
