7oon
From Proteopedia
(Difference between revisions)
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==The X-ray structure of heme-bound murine HEBP1== | ==The X-ray structure of heme-bound murine HEBP1== | ||
| - | <StructureSection load='7oon' size='340' side='right'caption='[[7oon]]' scene=''> | + | <StructureSection load='7oon' size='340' side='right'caption='[[7oon]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OON FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7oon]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OON FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oon OCA], [https://pdbe.org/7oon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oon RCSB], [https://www.ebi.ac.uk/pdbsum/7oon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oon ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oon OCA], [https://pdbe.org/7oon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oon RCSB], [https://www.ebi.ac.uk/pdbsum/7oon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oon ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HEBP1_MOUSE HEBP1_MOUSE] May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities.<ref>PMID:12413491</ref> <ref>PMID:16905545</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
[[Category: Birck C]] | [[Category: Birck C]] | ||
[[Category: Goodfellow BJ]] | [[Category: Goodfellow BJ]] | ||
[[Category: McEwen AG]] | [[Category: McEwen AG]] | ||
[[Category: Poussin-Courmontagne P]] | [[Category: Poussin-Courmontagne P]] | ||
Current revision
The X-ray structure of heme-bound murine HEBP1
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