7px4

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Current revision (13:10, 1 February 2024) (edit) (undo)
 
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<StructureSection load='7px4' size='340' side='right'caption='[[7px4]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='7px4' size='340' side='right'caption='[[7px4]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7px4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PX4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7px4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7PX4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8E2:Preladenant+conjugate+PSB-2113'>8E2</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8E2:Preladenant+conjugate+PSB-2113'>8E2</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7px4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7px4 OCA], [https://pdbe.org/7px4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7px4 RCSB], [https://www.ebi.ac.uk/pdbsum/7px4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7px4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7px4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7px4 OCA], [https://pdbe.org/7px4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7px4 RCSB], [https://www.ebi.ac.uk/pdbsum/7px4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7px4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
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[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 7px4" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 7px4" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Claff, T]]
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[[Category: Claff T]]
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[[Category: Klapschinski, T A]]
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[[Category: Klapschinski TA]]
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[[Category: Labahn, J]]
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[[Category: Labahn J]]
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[[Category: Muller, C E]]
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[[Category: Muller CE]]
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[[Category: Schlegel, J G]]
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[[Category: Schlegel JG]]
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[[Category: Subhramanyam, U K.Tiruttani]]
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[[Category: Tiruttani Subhramanyam UK]]
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[[Category: Vaassen, V J]]
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[[Category: Vaassen VJ]]
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[[Category: Vielmuth, C]]
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[[Category: Vielmuth C]]
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[[Category: Voss, J H]]
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[[Category: Voss JH]]
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[[Category: A2a]]
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[[Category: Adenosine receptor]]
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[[Category: G protein-coupled receptor]]
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[[Category: Gpcr]]
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[[Category: Membrane protein]]
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[[Category: Preladenant]]
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Current revision

Crystal structure of the adenosine A2A receptor (A2A-PSB1-bRIL) in complex with preladenant conjugate PSB-2113

PDB ID 7px4

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