This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


7qie

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:18, 1 February 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='7qie' size='340' side='right'caption='[[7qie]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
<StructureSection load='7qie' size='340' side='right'caption='[[7qie]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[7qie]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QIE FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[7qie]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QIE FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DVF:5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine'>DVF</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DVF:5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine'>DVF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qie OCA], [https://pdbe.org/7qie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qie RCSB], [https://www.ebi.ac.uk/pdbsum/7qie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qie ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qie OCA], [https://pdbe.org/7qie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qie RCSB], [https://www.ebi.ac.uk/pdbsum/7qie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qie ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/PI42C_HUMAN PI42C_HUMAN]] May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
+
[https://www.uniprot.org/uniprot/PI42C_HUMAN PI42C_HUMAN] May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Howard, T D]]
+
[[Category: Howard TD]]
-
[[Category: Ogg, D T]]
+
[[Category: Ogg DT]]
-
[[Category: Allosteric binding]]
+
-
[[Category: Lipid kinase]]
+
-
[[Category: Non-atp-competitive inhibitor]]
+
-
[[Category: Phosphatidylinositol 5-phosphate]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor

PDB ID 7qie

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/7qie"
Personal tools