This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7r4n
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='7r4n' size='340' side='right'caption='[[7r4n]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='7r4n' size='340' side='right'caption='[[7r4n]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[7r4n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R4N FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7r4n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R4N FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7RI:5-bromanyl-N-methyl-1H-indazole-3-carboxamide'>7RI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r4n OCA], [https://pdbe.org/7r4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r4n RCSB], [https://www.ebi.ac.uk/pdbsum/7r4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r4n ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r4n OCA], [https://pdbe.org/7r4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r4n RCSB], [https://www.ebi.ac.uk/pdbsum/7r4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r4n ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Glycolate oxidase 3D structures|Glycolate oxidase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bezerra | + | [[Category: Bezerra GA]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Bradley | + | [[Category: Bradley AR]] |
| - | [[Category: Brandeo-Neto | + | [[Category: Brandeo-Neto J]] |
| - | [[Category: Brennan | + | [[Category: Brennan PE]] |
| - | + | [[Category: Douangamath A]] | |
| - | [[Category: Douangamath | + | [[Category: Edwards A]] |
| - | [[Category: Edwards | + | [[Category: Krojer T]] |
| - | [[Category: Krojer | + | [[Category: Mackinnon S]] |
| - | [[Category: Mackinnon | + | [[Category: Oppermann U]] |
| - | [[Category: Oppermann | + | [[Category: Talon R]] |
| - | [[Category: Talon | + | [[Category: Yue WW]] |
| - | [[Category: Yue | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Structure of human hydroxyacid oxidase 1 bound with 5-bromo-N-methyl-1H-indazole-3-carboxamide
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bezerra GA | Bountra C | Bradley AR | Brandeo-Neto J | Brennan PE | Douangamath A | Edwards A | Krojer T | Mackinnon S | Oppermann U | Talon R | Yue WW | Von Delft F
