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2xsa

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Current revision (13:59, 1 February 2024) (edit) (undo)
 
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<StructureSection load='2xsa' size='340' side='right'caption='[[2xsa]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2xsa' size='340' side='right'caption='[[2xsa]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xsa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ocegh Ocegh]. The September 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''O-GlcNAc Transferase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_9 10.2210/rcsb_pdb/mom_2011_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XSA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xsa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oceanicola_granulosus_HTCC2516 Oceanicola granulosus HTCC2516]. The September 2011 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''O-GlcNAc Transferase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2011_9 10.2210/rcsb_pdb/mom_2011_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XSA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2xsb|2xsb]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xsa OCA], [https://pdbe.org/2xsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xsa RCSB], [https://www.ebi.ac.uk/pdbsum/2xsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xsa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xsa OCA], [https://pdbe.org/2xsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xsa RCSB], [https://www.ebi.ac.uk/pdbsum/2xsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xsa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q2CEE3_OCEGH Q2CEE3_OCEGH]] Cleaves GlcNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrate (in vitro).<ref>PMID:20863279</ref>
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[https://www.uniprot.org/uniprot/OGA_OCEGH OGA_OCEGH] Cleaves GlcNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrate (in vitro).<ref>PMID:20863279</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-N-acetylhexosaminidase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: O-GlcNAc Transferase]]
[[Category: O-GlcNAc Transferase]]
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[[Category: Ocegh]]
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[[Category: Oceanicola granulosus HTCC2516]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Aalten, D M.F van]]
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[[Category: Schuttelkopf AW]]
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[[Category: Schuttelkopf, A W]]
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[[Category: Van Aalten DMF]]
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[[Category: Glycosyl hydrolase]]
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[[Category: Hydrolase]]
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[[Category: O-glcnacase]]
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[[Category: O-glcnacylation]]
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PDB ID 2xsa

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