2xxp

From Proteopedia

(Difference between revisions)

Current revision

A widespread family of bacterial cell wall assembly proteins

Structural highlights

2xxp is a 1 chain structure with sequence from Streptococcus pneumoniae D39. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.692Å
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Q9ZII9_STRP2

Publication Abstract from PubMed

Teichoic acids and acidic capsular polysaccharides are major anionic cell wall polymers (APs) in many bacteria, with various critical cell functions, including maintenance of cell shape and structural integrity, charge and cation homeostasis, and multiple aspects of pathogenesis. We have identified the widespread LytR-Cps2A-Psr (LCP) protein family, of previously unknown function, as novel enzymes required for AP synthesis. Structural and biochemical analysis of several LCP proteins suggest that they carry out the final step of transferring APs from their lipid-linked precursor to cell wall peptidoglycan (PG). In Bacillus subtilis, LCP proteins are found in association with the MreB cytoskeleton, suggesting that MreB proteins coordinate the insertion of the major polymers, PG and AP, into the cell wall.

A widespread family of bacterial cell wall assembly proteins.,Kawai Y, Marles-Wright J, Cleverley RM, Emmins R, Ishikawa S, Kuwano M, Heinz N, Bui NK, Hoyland CN, Ogasawara N, Lewis RJ, Vollmer W, Daniel RA, Errington J EMBO J. 2011 Sep 30. doi: 10.1038/emboj.2011.358. PMID:21964069^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Kawai Y, Marles-Wright J, Cleverley RM, Emmins R, Ishikawa S, Kuwano M, Heinz N, Bui NK, Hoyland CN, Ogasawara N, Lewis RJ, Vollmer W, Daniel RA, Errington J. A widespread family of bacterial cell wall assembly proteins. EMBO J. 2011 Sep 30. doi: 10.1038/emboj.2011.358. PMID:21964069 doi:10.1038/emboj.2011.358

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2xxp"

@@ Line 3: / Line 3: @@
 <StructureSection load='2xxp' size='340' side='right'caption='[[2xxp]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2xxp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strp2 Strp2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XXP FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2xxp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_D39 Streptococcus pneumoniae D39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XXP FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DSL:MONO-TRANS,+OCTA-CIS+DECAPRENYL-PHOSPHATE'>DSL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.692&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2xxq|2xxq]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DSL:MONO-TRANS,+OCTA-CIS+DECAPRENYL-PHOSPHATE'>DSL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xxp OCA], [https://pdbe.org/2xxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xxp RCSB], [https://www.ebi.ac.uk/pdbsum/2xxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xxp ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q9ZII9_STRP2 Q9ZII9_STRP2]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 24: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Strp2]]
+[[Category: Streptococcus pneumoniae D39]]
-[[Category: Bui, N K]]
+[[Category: Bui NK]]
-[[Category: Cleverley, R M]]
+[[Category: Cleverley RM]]
-[[Category: Daniel, R A]]
+[[Category: Daniel RA]]
-[[Category: Emmins, R]]
+[[Category: Emmins R]]
-[[Category: Errington, J]]
+[[Category: Errington J]]
-[[Category: Heinz, N]]
+[[Category: Heinz N]]
-[[Category: Ishikawa, S]]
+[[Category: Ishikawa S]]
-[[Category: Kawai, Y]]
+[[Category: Kawai Y]]
-[[Category: Kuwano, M]]
+[[Category: Kuwano M]]
-[[Category: Lewis, R J]]
+[[Category: Lewis RJ]]
-[[Category: Marles-Wright, J]]
+[[Category: Marles-Wright J]]
-[[Category: Ogasawara, N]]
+[[Category: Ogasawara N]]
-[[Category: Vollmer, W]]
+[[Category: Vollmer W]]
-[[Category: Lcp]]
-[[Category: Lytr]]
-[[Category: Peptidoglycan]]
-[[Category: Replication]]

2xxp

From Proteopedia

Current revision

A widespread family of bacterial cell wall assembly proteins

Structural highlights

Function

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox