2yla

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Current revision (14:05, 1 February 2024) (edit) (undo)
 
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<StructureSection load='2yla' size='340' side='right'caption='[[2yla]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2yla' size='340' side='right'caption='[[2yla]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yla]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Strpn Strpn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YLA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yla]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_TIGR4 Streptococcus pneumoniae TIGR4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YLA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yl8|2yl8]], [[2yl9|2yl9]], [[2yl6|2yl6]], [[2yl5|2yl5]], [[2yll|2yll]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yla OCA], [https://pdbe.org/2yla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yla RCSB], [https://www.ebi.ac.uk/pdbsum/2yla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yla ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yla OCA], [https://pdbe.org/2yla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yla RCSB], [https://www.ebi.ac.uk/pdbsum/2yla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yla ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/STRH_STRPN STRH_STRPN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]]
*[[Beta-Hexosaminidase 3D structures|Beta-Hexosaminidase 3D structures]]
*[[Beta-Hexosaminidase 3D structures|Beta-Hexosaminidase 3D structures]]
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*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-N-acetylhexosaminidase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Strpn]]
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[[Category: Streptococcus pneumoniae TIGR4]]
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[[Category: Abbott, D W]]
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[[Category: Abbott DW]]
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[[Category: Boraston, A B]]
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[[Category: Boraston AB]]
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[[Category: Dalia, A B]]
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[[Category: Dalia AB]]
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[[Category: Deng, L]]
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[[Category: Deng L]]
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[[Category: Fairbanks, A J]]
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[[Category: Fairbanks AJ]]
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[[Category: Higgins, M A]]
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[[Category: Higgins MA]]
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[[Category: Parsons, T B]]
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[[Category: Parsons TB]]
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[[Category: Pluvinage, B]]
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[[Category: Pluvinage B]]
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[[Category: Robb, C]]
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[[Category: Robb C]]
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[[Category: Vocadlo, D J]]
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[[Category: Vocadlo DJ]]
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[[Category: Weiser, J N]]
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[[Category: Weiser JN]]
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[[Category: Hydrolase]]
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Current revision

INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS

PDB ID 2yla

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