5qcj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:10, 1 February 2024) (edit) (undo)
 
Line 1: Line 1:
==Crystal structure of human Cathepsin-S with bound ligand==
==Crystal structure of human Cathepsin-S with bound ligand==
-
<StructureSection load='5qcj' size='340' side='right'caption='[[5qcj]]' scene=''>
+
<StructureSection load='5qcj' size='340' side='right'caption='[[5qcj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QCJ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5qcj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QCJ FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qcj OCA], [https://pdbe.org/5qcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qcj RCSB], [https://www.ebi.ac.uk/pdbsum/5qcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qcj ProSAT]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BJY:5-hydroxy-3-{1-[(2S)-2-hydroxy-3-{5-(methylsulfonyl)-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propyl]piperidin-4-yl}-1H-pyrrolo[3,2-c]pyridin-5-ium'>BJY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qcj OCA], [https://pdbe.org/5qcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qcj RCSB], [https://www.ebi.ac.uk/pdbsum/5qcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qcj ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
==See Also==
==See Also==
Line 11: Line 15:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ameriks MK]]
[[Category: Ameriks MK]]

Current revision

Crystal structure of human Cathepsin-S with bound ligand

PDB ID 5qcj

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools