Tumor necrosis factor

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Current revision (11:08, 5 February 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
The biological assembly of human tumor necrosis factor is <scene name='55/551212/Cv/4'>homotetramer</scene> (PDB entry [[2az5]]). <scene name='55/551212/Cv/5'>Inhibitor binding site</scene>.
The biological assembly of human tumor necrosis factor is <scene name='55/551212/Cv/4'>homotetramer</scene> (PDB entry [[2az5]]). <scene name='55/551212/Cv/5'>Inhibitor binding site</scene>.
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== 3D Structures of tumor necrosis factor ==
== 3D Structures of tumor necrosis factor ==
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[[Tumor necrosis factor 3D structures]]
[[Tumor necrosis factor 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*TNF α
 
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**[[1tnf]] – hTNF – human <BR />
 
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**[[2tun]], [[1a8m]], [[4tsv]], [[5tsw]], [[2e7e]], [[2zjc]], [[2zpx]], [[5tsw]], [[5uui]], [[6rmj]] – hTNF (mutant) <BR />
 
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**[[2az5]], [[5mu8]], [[6ooy]], [[6ooz]], [[6op0]] – hTNF + inhibitor <BR />
 
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**[[3it8]] – hTNF + poxvirus 2L protein <BR />
 
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**[[3l9j]] – hTNF + antagonist <BR />
 
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**[[3alq]] – hTNF (mutant) + TNF receptor <BR />
 
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**[[4g3y]], [[3wd5]] – hTNF + antibody <BR />
 
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**[[4twt]] – hTNF + peptide <BR />
 
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**[[2tnf]] – mTNF – mouse <BR />
 
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**[[7kp7]], [[7kp8]] – mTNF + hTNFR1A <BR />
 
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**[[7kpb]] – mTNF + hTNFR1A + antibody<BR />
 
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*TNF β
 
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**[[1tnr]] – hTNF + TNF receptor p55 <BR />
 
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*TNF
 
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**[[2vfj]] – hTNF ovarian tumor domain <BR />
 
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**[[5m2i]], [[5m2j]], [[5m2m]], [[5wux]], [[5yoy]] – hTNF + antibody <BR />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
</StructureSection>
</StructureSection>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Structure of human tumor necrosis factor tetramer complex with inhibitor (PDB entry 2az5)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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