1ei6

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Current revision (07:03, 7 February 2024) (edit) (undo)
 
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<StructureSection load='1ei6' size='340' side='right'caption='[[1ei6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1ei6' size='340' side='right'caption='[[1ei6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ei6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_fluorescens_liquefaciens"_flugge_1886 "bacillus fluorescens liquefaciens" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EI6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ei6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_fluorescens Pseudomonas fluorescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EI6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EI6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PPF:PHOSPHONOFORMIC+ACID'>PPF</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphonoacetate_hydrolase Phosphonoacetate hydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.11.1.2 3.11.1.2] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PPF:PHOSPHONOFORMIC+ACID'>PPF</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ei6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ei6 OCA], [https://pdbe.org/1ei6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ei6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ei6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ei6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ei6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ei6 OCA], [https://pdbe.org/1ei6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ei6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ei6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ei6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PHNHY_PSEFL PHNHY_PSEFL]] Specifically hydrolyzes phosphonoacetate. Does not have activity on other organophosphonates or acetates.<ref>PMID:8288524</ref>
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[https://www.uniprot.org/uniprot/PHNHY_PSEFL PHNHY_PSEFL] Specifically hydrolyzes phosphonoacetate. Does not have activity on other organophosphonates or acetates.<ref>PMID:8288524</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus fluorescens liquefaciens flugge 1886]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Phosphonoacetate hydrolase]]
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[[Category: Pseudomonas fluorescens]]
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[[Category: Benning, M M]]
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[[Category: Benning MM]]
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[[Category: Dunaway-Mariano, D]]
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[[Category: Dunaway-Mariano D]]
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[[Category: Holden, H M]]
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[[Category: Holden HM]]
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[[Category: Kim, A D]]
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[[Category: Kim AD]]
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[[Category: Hydrolase]]
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[[Category: Phosphonoacetate]]
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[[Category: Zinc]]
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Current revision

CRYSTAL STRUCTURE OF PHOSPHONOACETATE HYDROLASE COMPLEXED WITH PHOSPHONOFORMATE

PDB ID 1ei6

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