1i2l

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Current revision (07:32, 7 February 2024) (edit) (undo)
 
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<StructureSection load='1i2l' size='340' side='right'caption='[[1i2l]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1i2l' size='340' side='right'caption='[[1i2l]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1i2l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2L OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1I2L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1i2l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I2L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I2L FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCS:D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE'>DCS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PABC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCS:D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE'>DCS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1i2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i2l OCA], [http://pdbe.org/1i2l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1i2l RCSB], [http://www.ebi.ac.uk/pdbsum/1i2l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1i2l ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i2l OCA], [https://pdbe.org/1i2l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i2l RCSB], [https://www.ebi.ac.uk/pdbsum/1i2l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i2l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PABC_ECOLI PABC_ECOLI]] Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate.<ref>PMID:1644759</ref> <ref>PMID:2251281</ref>
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[https://www.uniprot.org/uniprot/PABC_ECOLI PABC_ECOLI] Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate.<ref>PMID:1644759</ref> <ref>PMID:2251281</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Eisenstein, E]]
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[[Category: Eisenstein E]]
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[[Category: Fisher, K E]]
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[[Category: Fisher KE]]
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[[Category: Howard, A J]]
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[[Category: Howard AJ]]
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[[Category: Jensen, P Y]]
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[[Category: Jensen PY]]
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[[Category: Ladner, J E]]
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[[Category: Ladner JE]]
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[[Category: Pachikara, A S]]
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[[Category: Pachikara AS]]
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[[Category: Parsons, J F]]
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[[Category: Parsons JF]]
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[[Category: Tordova, M]]
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[[Category: Tordova M]]
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[[Category: Aminodeoxychorismate]]
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[[Category: D-cycloserine]]
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[[Category: Lyase]]
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[[Category: Pabc]]
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[[Category: Pyridoxal phosphate]]
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Current revision

DEOXYCHORISMATE LYASE FROM ESCHERICHIA COLI WITH INHIBITOR

PDB ID 1i2l

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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