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8a68
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[8a68]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A68 FirstGlance]. <br> | <table><tr><td colspan='2'>[[8a68]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A68 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A68 FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L7U:~{N}-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]-1-[(2~{R})-2-(6-methoxynaphthalen-2-yl)propanoyl]piperidine-4-carboxamide'>L7U</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L7U:~{N}-[2-[2-(dimethylamino)ethyldisulfanyl]ethyl]-1-[(2~{R})-2-(6-methoxynaphthalen-2-yl)propanoyl]piperidine-4-carboxamide'>L7U</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a68 OCA], [https://pdbe.org/8a68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a68 RCSB], [https://www.ebi.ac.uk/pdbsum/8a68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a68 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a68 OCA], [https://pdbe.org/8a68 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a68 RCSB], [https://www.ebi.ac.uk/pdbsum/8a68 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a68 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
Current revision
Small molecule stabilizer (compound 5) for C-RAF(pS259) and 14-3-3
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Categories: Homo sapiens | Large Structures | Arkin MR | Brunsveld L | Centorrino F | Kenanova DN | Neitz J | Ottmann C | Sijbesma E | Vickery H | Virta J | Visser EJ | Zhong M
