1q3i

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[[Image:1q3i.jpg|left|200px]]
[[Image:1q3i.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1q3i |SIZE=350|CAPTION= <scene name='initialview01'>1q3i</scene>, resolution 2.6&Aring;
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The line below this paragraph, containing "STRUCTURE_1q3i", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Sodium/potassium-exchanging_ATPase Sodium/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.9 3.6.3.9] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1q3i| PDB=1q3i | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1q3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q3i OCA], [http://www.ebi.ac.uk/pdbsum/1q3i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1q3i RCSB]</span>
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}}
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'''Crystal Structure of Na,K-ATPase N-domain'''
'''Crystal Structure of Na,K-ATPase N-domain'''
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==About this Structure==
==About this Structure==
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1Q3I is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3I OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3I OCA].
==Reference==
==Reference==
The crystallographic structure of Na,K-ATPase N-domain at 2.6A resolution., Hakansson KO, J Mol Biol. 2003 Oct 3;332(5):1175-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14499619 14499619]
The crystallographic structure of Na,K-ATPase N-domain at 2.6A resolution., Hakansson KO, J Mol Biol. 2003 Oct 3;332(5):1175-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14499619 14499619]
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[[Category: Protein complex]]
 
[[Category: Sodium/potassium-exchanging ATPase]]
[[Category: Sodium/potassium-exchanging ATPase]]
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[[Category: Sus scrofa]]
 
[[Category: Hakansson, K O.]]
[[Category: Hakansson, K O.]]
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[[Category: anti-parallel beta sheet]]
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[[Category: Anti-parallel beta sheet]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:49:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:08:19 2008''
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Revision as of 02:49, 3 May 2008

Image:1q3i.jpg

Template:STRUCTURE 1q3i

Crystal Structure of Na,K-ATPase N-domain


Overview

The structure of the N-domain of porcine alpha(2) Na,K-ATPase was determined crystallographically to 3.2A resolution by isomorphous heavy-atom replacement using a single mercury derivative. The structure was finally refined against 2.6A resolution synchrotron data. The domain forms a seven-stranded antiparallel beta-sheet with two additional beta-strands forming a hairpin and five alpha-helices. Approximately 75% of the residues were superimposable with residues from the structure of Ca-ATPase N-domain, and a structure-based sequence alignment is presented. The positions of key residues are discussed in relation to the pattern of hydrophobicity, charge and sequence conservation of the molecular surface. The structure of a hexahistidine tag binding to nickel ions is presented.

About this Structure

Full crystallographic information is available from OCA.

Reference

The crystallographic structure of Na,K-ATPase N-domain at 2.6A resolution., Hakansson KO, J Mol Biol. 2003 Oct 3;332(5):1175-82. PMID:14499619 Page seeded by OCA on Sat May 3 05:49:20 2008

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