This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1q3i
From Proteopedia
| Line 1: | Line 1: | ||
[[Image:1q3i.jpg|left|200px]] | [[Image:1q3i.jpg|left|200px]] | ||
| - | + | <!-- | |
| - | + | The line below this paragraph, containing "STRUCTURE_1q3i", creates the "Structure Box" on the page. | |
| - | + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | |
| - | + | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |
| - | + | or leave the SCENE parameter empty for the default display. | |
| - | | | + | --> |
| - | | | + | {{STRUCTURE_1q3i| PDB=1q3i | SCENE= }} |
| - | + | ||
| - | + | ||
| - | }} | + | |
'''Crystal Structure of Na,K-ATPase N-domain''' | '''Crystal Structure of Na,K-ATPase N-domain''' | ||
| Line 19: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | + | Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q3I OCA]. | |
==Reference== | ==Reference== | ||
The crystallographic structure of Na,K-ATPase N-domain at 2.6A resolution., Hakansson KO, J Mol Biol. 2003 Oct 3;332(5):1175-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14499619 14499619] | The crystallographic structure of Na,K-ATPase N-domain at 2.6A resolution., Hakansson KO, J Mol Biol. 2003 Oct 3;332(5):1175-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14499619 14499619] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Sodium/potassium-exchanging ATPase]] | [[Category: Sodium/potassium-exchanging ATPase]] | ||
| - | [[Category: Sus scrofa]] | ||
[[Category: Hakansson, K O.]] | [[Category: Hakansson, K O.]] | ||
| - | [[Category: | + | [[Category: Anti-parallel beta sheet]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 05:49:20 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 02:49, 3 May 2008
Crystal Structure of Na,K-ATPase N-domain
Overview
The structure of the N-domain of porcine alpha(2) Na,K-ATPase was determined crystallographically to 3.2A resolution by isomorphous heavy-atom replacement using a single mercury derivative. The structure was finally refined against 2.6A resolution synchrotron data. The domain forms a seven-stranded antiparallel beta-sheet with two additional beta-strands forming a hairpin and five alpha-helices. Approximately 75% of the residues were superimposable with residues from the structure of Ca-ATPase N-domain, and a structure-based sequence alignment is presented. The positions of key residues are discussed in relation to the pattern of hydrophobicity, charge and sequence conservation of the molecular surface. The structure of a hexahistidine tag binding to nickel ions is presented.
About this Structure
Full crystallographic information is available from OCA.
Reference
The crystallographic structure of Na,K-ATPase N-domain at 2.6A resolution., Hakansson KO, J Mol Biol. 2003 Oct 3;332(5):1175-82. PMID:14499619 Page seeded by OCA on Sat May 3 05:49:20 2008
