333d
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=333D FirstGlance]. <br> | <table><tr><td colspan='2'>[[333d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=333D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=333D FirstGlance]. <br> | ||
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.52Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [https://pdbe.org/333d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [https://www.ebi.ac.uk/pdbsum/333d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=333d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=333d OCA], [https://pdbe.org/333d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=333d RCSB], [https://www.ebi.ac.uk/pdbsum/333d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=333d ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The X-ray crystallographic structure of the RNA duplex [r(CGCAIGCG)]2 has been refined to 2.5 A. It shows a symmetric internal loop of two non-Watson-Crick base pairs which form in the middle of the duplex. The tandem A-I/I-A pairs are related by a crystallographic two-fold axis. Both A(anti)-I(anti) mismatches are in a head-to-head conformation forming hydrogen bonds using the Watson-Crick positions. The octamer duplexes stack above one another in the cell forming a pseudo-infinite helix throughout the crystal. A hydrated calcium ion bridges between the 3'-terminal of one molecule and the backbone of another. The tandem A-I mismatches are incorporated with only minor distortion to the backbone. This is in contrast to the large helical perturbations often produced by sheared G-A pairs in RNA oligonucleotides. | ||
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| - | The crystal structure of an RNA oligomer incorporating tandem adenosine-inosine mismatches.,Carter RJ, Baeyens KJ, SantaLucia J, Turner DH, Holbrook SR Nucleic Acids Res. 1997 Oct 15;25(20):4117-22. PMID:9321667<ref>PMID:9321667</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 333d" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Baeyens | + | [[Category: Baeyens KJ]] |
| - | [[Category: Carter | + | [[Category: Carter RJ]] |
| - | [[Category: Holbrook | + | [[Category: Holbrook SR]] |
| - | [[Category: SantaLucia | + | [[Category: SantaLucia Jr J]] |
| - | [[Category: Turner | + | [[Category: Turner DH]] |
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Current revision
THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES
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