3jb8

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Current revision (08:42, 7 February 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3jb8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Maize_chlorotic_mottle_virus Maize chlorotic mottle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JB8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3jb8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Maize_chlorotic_mottle_virus Maize chlorotic mottle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JB8 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jb8 OCA], [https://pdbe.org/3jb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jb8 RCSB], [https://www.ebi.ac.uk/pdbsum/3jb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jb8 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jb8 OCA], [https://pdbe.org/3jb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jb8 RCSB], [https://www.ebi.ac.uk/pdbsum/3jb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jb8 ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/I6QQC4_MCMV I6QQC4_MCMV]
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Maize chlorotic mottle virus (MCMV) is the only member of the Machlomovirus genus in the family Tombusviridae. Here, we obtained the Cryo-EM structure of MCMV by single particle analysis with most local resolution at approximately 4 A. The Calpha backbone was built based on residues with bulky side chains. The resolved C-terminus of the capsid protein subunit and obvious openings at the 2-fold axis demonstrated the compactness of the asymmetric unit, which indicates an important role in the stability of MCMV. The Asp116 residue from each subunit around the 5-fold and 3-fold axes contributed to the negative charges in the centers of the pentamers and hexamers, which might serve as a solid barrier against the leakage of genomic RNA. Finally, the loops most exposed on the surface were analyzed and are proposed to be potential functional sites related to MCMV transmission.
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Insight into the three-dimensional structure of maize chlorotic mottle virus revealed by Cryo-EM single particle analysis.,Wang CY, Zhang QF, Gao YZ, Zhou XP, Ji G, Huang XJ, Hong J, Zhang CX Virology. 2015 Nov;485:171-8. doi: 10.1016/j.virol.2015.07.014. Epub 2015 Aug 11. PMID:26275511<ref>PMID:26275511</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3jb8" style="background-color:#fffaf0;"></div>
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==See Also==
==See Also==
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</SX>
</SX>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Maize chlorotic mottle virus]]
[[Category: Maize chlorotic mottle virus]]
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[[Category: Gao, Y Z]]
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[[Category: Gao YZ]]
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[[Category: Hong, J]]
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[[Category: Hong J]]
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[[Category: Huang, X J]]
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[[Category: Huang XJ]]
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[[Category: Ji, G]]
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[[Category: Ji G]]
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[[Category: Wang, C Y]]
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[[Category: Wang CY]]
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[[Category: Zhang, C X]]
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[[Category: Zhang CX]]
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[[Category: Zhang, Q F]]
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[[Category: Zhang QF]]
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[[Category: Zhou, X P]]
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[[Category: Zhou XP]]
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[[Category: Icosahedral virus]]
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[[Category: Mcmv]]
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[[Category: Single particle analysis]]
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[[Category: Three-dimensional structure]]
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[[Category: Transmission]]
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[[Category: Virus]]
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Current revision

Insight into Three-dimensional structure of Maize Chlorotic Mottle Virus Revealed by Single Particle Analysis

3jb8, resolution 3.60Å

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OCA

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