3ko6

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Current revision (08:45, 7 February 2024) (edit) (undo)
 
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<StructureSection load='3ko6' size='340' side='right'caption='[[3ko6]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='3ko6' size='340' side='right'caption='[[3ko6]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ko6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KO6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ko6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KO6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YKL069W ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SME:METHIONINE+SULFOXIDE'>SME</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-methionine_(R)-S-oxide_reductase L-methionine (R)-S-oxide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.4.14 1.8.4.14] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ko6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ko6 OCA], [https://pdbe.org/3ko6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ko6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ko6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ko6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ko6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ko6 OCA], [https://pdbe.org/3ko6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ko6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ko6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ko6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FRMSR_YEAST FRMSR_YEAST]] Catalyzes the reversible oxidation-reduction of the R-enantiomer of free methionine sulfoxide to methionine. Does not act on S-enantiomer of free methionine sulfoxide or R-enantiomer of dabsylated methionine sulfoxide. Involved in protection against oxidative stress.<ref>PMID:19049972</ref>
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[https://www.uniprot.org/uniprot/FRMSR_YEAST FRMSR_YEAST] Catalyzes the reversible oxidation-reduction of the R-enantiomer of free methionine sulfoxide to methionine. Does not act on S-enantiomer of free methionine sulfoxide or R-enantiomer of dabsylated methionine sulfoxide. Involved in protection against oxidative stress.<ref>PMID:19049972</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Baker's yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chen, Y]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Guo, P C]]
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[[Category: Chen Y]]
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[[Category: Ma, X X]]
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[[Category: Guo P-C]]
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[[Category: Zhou, C Z]]
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[[Category: Ma X-X]]
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[[Category: Catalytic mechanism]]
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[[Category: Zhou C-Z]]
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[[Category: Methionine-r-sulfoxide reductase]]
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[[Category: Oxidoreductase]]
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[[Category: Product dissociation]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Substrate binding]]
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Current revision

Crystal structure of yeast free methionine-R-sulfoxide reductase Ykg9 in complex with the substrate

PDB ID 3ko6

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