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5qi2

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Current revision (08:55, 7 February 2024) (edit) (undo)
 
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<StructureSection load='5qi2' size='340' side='right'caption='[[5qi2]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
<StructureSection load='5qi2' size='340' side='right'caption='[[5qi2]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5qi2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QI2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QI2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5qi2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QI2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QI2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GUV:1-methyl-3-[3-(2-methylpyrimidin-4-yl)phenyl]urea'>GUV</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GUV:1-methyl-3-[3-(2-methylpyrimidin-4-yl)phenyl]urea'>GUV</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qi2 OCA], [http://pdbe.org/5qi2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qi2 RCSB], [http://www.ebi.ac.uk/pdbsum/5qi2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qi2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qi2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qi2 OCA], [https://pdbe.org/5qi2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qi2 RCSB], [https://www.ebi.ac.uk/pdbsum/5qi2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qi2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN]] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.
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[https://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.
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==See Also==
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*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Brandao-Neto, J]]
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[[Category: Brandao-Neto J]]
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[[Category: Delft, F von]]
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[[Category: Douangamath A]]
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[[Category: Douangamath, A]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Elkins J]]
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[[Category: Elkins, J]]
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[[Category: Kessler B]]
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[[Category: Kessler, B]]
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[[Category: Knapp S]]
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[[Category: Knapp, S]]
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[[Category: Krojer T]]
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[[Category: Krojer, T]]
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[[Category: Schuler H]]
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[[Category: Schuler, H]]
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[[Category: Schuller M]]
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[[Category: Schuller, M]]
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[[Category: Talon R]]
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[[Category: Talon, R]]
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[[Category: Zhang R]]
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[[Category: Zhang, R]]
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[[Category: Von Delft F]]
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[[Category: Macrodomain]]
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[[Category: Pandda]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Transferase]]
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[[Category: Xchemexplorer]]
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Current revision

PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000110a

PDB ID 5qi2

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