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5qju

From Proteopedia

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Current revision (08:56, 7 February 2024) (edit) (undo)
 
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<StructureSection load='5qju' size='340' side='right'caption='[[5qju]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
<StructureSection load='5qju' size='340' side='right'caption='[[5qju]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5qju]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QJU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5QJU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5qju]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QJU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QJU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K2G:5-chloro-2-(propan-2-yl)pyrimidine-4-carboxamide'>K2G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5qju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qju OCA], [http://pdbe.org/5qju PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qju RCSB], [http://www.ebi.ac.uk/pdbsum/5qju PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qju ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K2G:5-chloro-2-(propan-2-yl)pyrimidine-4-carboxamide'>K2G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qju OCA], [https://pdbe.org/5qju PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qju RCSB], [https://www.ebi.ac.uk/pdbsum/5qju PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qju ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN]] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref>
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[https://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Burgess-Brown, N]]
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[[Category: Burgess-Brown N]]
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[[Category: Collins, P]]
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[[Category: Collins P]]
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[[Category: Delft, F von]]
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[[Category: Dubianok Y]]
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[[Category: Dubianok, Y]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Huber K]]
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[[Category: Huber, K]]
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[[Category: Krojer T]]
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[[Category: Krojer, T]]
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[[Category: Strain-Damerell C]]
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[[Category: Strain-Damerell, C]]
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[[Category: Wright N]]
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[[Category: Wright, N]]
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[[Category: Von Delft F]]
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[[Category: Hydrolase]]
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[[Category: Nudt5]]
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[[Category: Pandda]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Xchemexplorer]]
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Current revision

PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT5 in complex with Z906021418

PDB ID 5qju

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