8y0s

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m (Protected "8y0s" [edit=sysop:move=sysop])
Current revision (07:24, 14 February 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8y0s is ON HOLD
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==Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor==
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<StructureSection load='8y0s' size='340' side='right'caption='[[8y0s]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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Authors: Kamo, T., Kuroda, K., Nimura, S., Guo, Y., Kondo, S., Nukaga, M., Hoshino, T.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8y0s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y0S FirstGlance]. <br>
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Description: Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1LXO:3-[2-azanyl-5-[2-cyclohexylethyl-[3-(4-methylphenoxy)propyl]amino]phenyl]propanoic+acid'>A1LXO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Guo, Y]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y0s OCA], [https://pdbe.org/8y0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y0s RCSB], [https://www.ebi.ac.uk/pdbsum/8y0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y0s ProSAT]</span></td></tr>
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[[Category: Kamo, T]]
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</table>
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[[Category: Kondo, S]]
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== Function ==
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[[Category: Nimura, S]]
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[https://www.uniprot.org/uniprot/BLAB_SERMA BLAB_SERMA] Confers resistance to imipenem and broad-spectrum beta-lactams. Also hydrolyzes carbapenems.
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[[Category: Nukaga, M]]
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__TOC__
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[[Category: Hoshino, T]]
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</StructureSection>
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[[Category: Kuroda, K]]
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[[Category: Large Structures]]
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[[Category: Serratia marcescens]]
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[[Category: Guo Y]]
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[[Category: Hoshino T]]
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[[Category: Kamo T]]
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[[Category: Kondo S]]
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[[Category: Kuroda K]]
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[[Category: Nimura S]]
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[[Category: Nukaga M]]

Current revision

Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor

PDB ID 8y0s

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