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8y6b
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of human LGI1-ADAM22 complex in space group P212121== | |
| - | + | <StructureSection load='8y6b' size='340' side='right'caption='[[8y6b]], [[Resolution|resolution]] 3.49Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8y6b]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Y6B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Y6B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.49Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8y6b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8y6b OCA], [https://pdbe.org/8y6b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8y6b RCSB], [https://www.ebi.ac.uk/pdbsum/8y6b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8y6b ProSAT]</span></td></tr> |
| - | [[Category: Liu | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ADA22_HUMAN ADA22_HUMAN] Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.<ref>PMID:12589811</ref> <ref>PMID:15882968</ref> <ref>PMID:16385342</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Liu H]] | ||
| + | [[Category: Xu F]] | ||
Current revision
Structure of human LGI1-ADAM22 complex in space group P212121
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